Protection from cervical cancer
All you need to know about the HPV vaccine and the school-based vaccination campaign

What is cervical cancer and HPV?
Important
Ensure you have completed your child’s vaccination consent form. Without consent from a guardian, girls will not be able to receive their free HPV vaccination. Schools will provide qualifying learners with consent forms to take home for their parents to complete. For more information contact your child’s school.
2023 School-based HPV vaccination
The 2023 HPV vaccination campaign started in February and is delivering the first dose to Grade 5 girls nine years and older at government schools around South Africa. Vaccination teams will return in September to provide a second dose. Both doses are free. Girls need two doses of the HPV vaccine to be fully protected against cervical cancer and it is important that they receive their second dose.
The HPV school-based vaccination programme will take place at the same time as the national measles campaign – which will also be administered in schools. It is safe for a girl to get the HPV vaccine and the measles vaccine at the same time.
Cervical cancer is the second most common cancer among women in South Africa, after breast cancer. It is the leading cause of cancer deaths among women in South Africa, particularly among adolescents and women aged 15 to 44.
Over 5,000 new cases of cervical cancer are reported each year in South Africa, with most of these cases being fatal.
Cervical cancer is mainly caused by the infection of the cervix by the Human Papillomavirus (HPV), which is sexually transmitted. The cervix is the lower part of the womb.
Infection with the human papillomavirus (HPV) significantly increases the risk of developing cervical cancer later in life. There is no treatment for the virus itself, but there are treatments for the health problems that HPV can cause. The risk of infection and developing cervical cancer is much higher for girls and women living with HIV. Getting the HPV vaccine protects girls now and ensures that they remain protected from cervical cancer later in life.
How can I get protected against cervical cancer?
Vaccination against HPV is the most effective prevention method against cervical cancer. Prevention and control of cervical cancer is part of a broad-based Sexual and Reproductive Health (SRH) programme implemented by the national Department of Health.
The World Health Organization recommends that the HPV vaccine is administered to girls between the ages of 9 and 12, before they are sexually active and therefore exposed to sexually transmitted infections (STI) like the HPV virus.
The HPV vaccine is administered in two doses, about 6 months apart. It is most effective in preventing the types of HPV that are the most common causes of cervical cancer and is safe for use.
How safe and effective is the vaccine?
The HPV vaccine used in South Africa is very safe and effective in preventing the HPV-16 and HPV-18 strains of the virus, which cause most cases of cervical cancer. Millions of girls have received the HPV vaccine without any serious side effects.
Where can I get the HPV vaccine for my child?
In 2014, the South African government introduced free vaccinations against HPV to girls in public schools through the Integrated School Health Programme.
Health officials from the Department of Health visit government schools to carry out the HPV vaccination campaign. In 2023, the campaign aims to vaccinate all Grade 5 girls who are 9 years and older.
For a child to receive their vaccination, and be protected against cervical cancer and measles, parents or caregivers need to fill in and sign the consent forms which they will receive from their child’s school. No girl will be vaccinated without parental consent.
For more information contact your school or your health care provider, or the National Health Hotline 0800 029 999
For further information about cervical cancer see the World Health Organisation
What is the human papillomavirus (HPV)?
HPV (human papillomavirus) is a common sexually transmitted infection, which affects most people at some point in their lives. There are many different types of HPV. Some types cause health problems including genital warts and cancers. But there is a vaccine that can prevent these health problems.
Who can get the human papillomavirus (HPV)?
Both women and men who are sexually active can get HPV. The most common mode of transmission is through sex, but it can also be transmitted through any form of skin-to-skin contact and from mother to child. HPV can be passed even when an infected person has no signs or symptoms.
Is it possible to tell if a person has HPV just by looking at them?
No. The HPV infection cannot be seen and, in most cases, there are no visible signs.
I am pregnant. Will having HPV affect my pregnancy?
If you are pregnant and have HPV, you can get genital warts or develop abnormal cell changes on your cervix. Abnormal cell changes can be found with routine cervical cancer screening. You should undergo routine cervical cancer screening even when you are pregnant.
Are HPV and HIV the same?
No. HPV should not be confused with HIV. They are both viruses, but they are completely different in how they affect the human body.
Does HPV cause cancer?
HPV can cause cervical cancer and other cancers including cancer of the vulva, penis, or anus. It can also cause cancer in the back of the throat, including the base of the tongue and tonsils.
What is cervical cancer?
Cervical cancer is a cancer that affects the cervix, which is the lower part (known as the mouth) of the womb. According to the South African Medical Research Council, cervical cancer is the leading cause of cancer among women aged 15 to 44 years in South Africa. Cancer is when abnormal cells in the human body start to grow very quickly and cannot be controlled by normal body processes. Over time, normal cells are replaced by cancer cells, and without early diagnosis and treatment the person may die.
How can you confirm if a person has cervical cancer?
This depends on what is called the stage of the disease. Women with early-stage cancer may not experience any signals of disease. In these cases, a special test is required to detect if a person has early signs of developing cervical cancer, called a cervical screening test. The cells from the cervix are collected and sent to a laboratory for testing and confirmation. In the later and progressive stages of the disease, women may start experiencing abnormal bleeding, vaginal discharge, bleeding after intercourse, and loss of control of urine.
Has the HPV vaccine been thoroughly tested and used before?
The HPV vaccine is safe and most effective when provided from age nine or before girls become sexually active. In South Africa, the HPV vaccination was approved by the South African Health Products Regulatory Authority in 2008 for its efficacy and safety.
Will I get HPV infection from the HPV vaccine?
No. The vaccine is non-infectious, and you will not get HPV infection through vaccination.
Why should girls be vaccinated against HPV?
The HPV vaccine is important to protect against HPV infection that could lead to cervical cancer later in life.
How many doses of the HPV vaccine are needed?
Two doses (a minimum of five months apart) are offered free of charge to girls 9 years and older in special schools or in Grade 5 to be fully protected.
What are the side effects of the HPV vaccine?
Possible side effects include:
- Pain, redness, or swelling in the arm where the shot was given
- Fever
- Dizziness
- Nausea
- Headache or feeling tired
- Muscle or joint pain
Do girls need consent from their parents or caregivers to be vaccinated?
Yes. Parents or caregivers need to provide signed consent for the vaccination of the girls. For consent to be valid, it must be informed, understood and voluntary, and the person consenting must have the capacity to make the decision.
Why are only Grade 5 girls being vaccinated during this campaign?
This vaccine is most effective if provided before a person is exposed to the (sexually transmitted) virus. It is registered for use in boys and girls from the age of nine. As the entry requirement for Grade 1 is 6 years, most girls in Grade 5 will be between 9 and 11 years old. Therefore, Grade 5 has been identified as the most suitable grade to commence the vaccination.
Who will be conducting the vaccination?
Trained teams of healthcare workers will be administering the vaccination.
If a girl or woman does not meet the criteria or missed the HPV school-based vaccination, what can be done to protect her from cervical cancer?
HPV vaccines are available in the private sector from a doctor or pharmacy. However, they are not free of charge. If she is already at risk of having contracted HPV, it is recommended that she has routine screening tests.
Can boys get the HPV vaccine?
The school-based HPV vaccination campaign is currently available to girls only. However, boys aged 9 and older, are encouraged to get the HPV vaccine and caregivers should approach their general practitioner to find out more.
If my child is in a private school, where can we go to get the HPV vaccine?
If your child is at a school where the government school health teams do not come to provide vaccination and other services (e.g. private and independent schools); please take your child to the doctor who will advise accordingly.