Conflict in Jonglei, Unity and Eastern Equatoria States.
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Renewed hostilities between the South Sudan People’s Defense Forces (SSPDF) and the Sudan People’s Liberation Army–In Opposition (SPLA-IO) have intensified across northern and central South Sudan since late December 2025.
Humanitarian access has been critically hindered by insecurity, movement restrictions, and no-fly zones imposed in opposition-held areas since 1 January, leaving air operations curtailed and supply routes to the most affected counties severely strained. Despite these constraints, authorities approved a one-day humanitarian flight window on 2 February, enabling UNICEF and partners to relocate staff and deliver 2.5 metric tons of lifesaving health and nutrition supplies to Akobo, followed by a second limited window on 5 February for additional therapeutic commodities. At the same time, cholera treatment centres in Jonglei remain overwhelmed.
