Symptoms to watch after Rotavirus Vaccination

How can you detect normal and abnormal signs? What should parents do to ensure the child’s safety?

Ministry of Health and UNICEF Viet Nam
Symptoms to watch after rotavirus vaccination
Nguyen Ba Doan
04 March 2025

The Rotavirus vaccine is an effective "shield" that helps protect young children from the dangerous risk of acute diarrhoea. However, like other vaccines, children may experience some side effects after receiving the vaccine. How can you detect normal and abnormal signs? What should parents do to ensure the child’s safety? Let’s explore the detailed information below.

Similar to medication, children who receive the Rotavirus vaccine may experience side effects. However, these symptoms are usually mild and resolve on their own. Serious side effects can occur, but they are rare. Parents can be reassured if the child shows signs like irritability (crying), mild temporary diarrhoea or vomiting.

What signs should be watched for after children receive the Rotavirus vaccine?

Parents and caregivers should monitor the child’s overall condition, including their mental state, appetite, sleep patterns, temperature and any rashes. If the child has a fever, measure her/his temperature.

Take the child immediately to a health facility if any of the following signs are observed:

  • Mental state: persistent crying, increased stimulus response, drowsiness...

  • Breathing difficulties: chest indrawing, bluish lips, laboured breathing.

  • High fever over 39°C, difficulty reducing the temperature, or fever lasting longer than 24 hours.

  • Bluish mottling of the skin, cold extremities.

  • Repeated vomiting, refusal to eat, poor feeding, or refusal to breastfeed.

  • Convulsions

  • Skin rashes

  • Signs of suspected intussusception in children: Severe abdominal pain (crying in spasms), prolonged vomiting, blood in the stool, abdominal bloating.

  • Or if the child shows any other abnormal signs.

Receiving the Rotavirus vaccine is an essential step in protecting children from the severe risks of acute diarrhoea caused by the Rota virus. However, the role of parents extends beyond simply bringing the child to the health facility; it also involves observing and caring for the child after vaccination. A full understanding of the potential side effects and abnormal signs will help ensure that the child remains safe and well-protected.